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10 Apr 12:30

A concise total synthesis of cochlearoid B

Org. Biomol. Chem., 2018, 16,3358-3361
DOI: 10.1039/C8OB00615F, Communication
Wuxia Zhang, Dehai Xiao, Bo Wang
A T-type calcium channel inhibiting natural product cochlearoid B was synthesized in 7 linear steps.
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15 Jul 17:48

Catalytic Enantioselective Conjugate Alkynylation of β-Aryl-β-trifluoromethyl Enones Constructing Propargylic All-Carbon Quaternary Stereogenic Centers

by Amparo Sanz-Marco, Gonzalo Blay, Carlos Vila and José R. Pedro

TOC Graphic

Organic Letters
DOI: 10.1021/acs.orglett.6b01494